Secretary of State Antony Blinken on Friday said the U.S. had no involvement in the apparent attack on Iran.
The strikes hours earlier appeared to be retaliation by Israel, but the Jewish State did not formally take responsibility for the apparent attack.
Mr. Blinken did not get into specifics about who was responsible.
“I’m not going to speak to that except to say that the United States has not been involved in any offensive operations,” he said at a press conference in Italy.
He said the U.S. priority is de-escalation and “avoiding conflict.”
“That remains our focus,” he said.
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The attack overnight at a military base near the city of Isfahan seems to have been limited in scope, perhaps a sign that Israel and Iran want to pull back from the brink of war.
Explosions also were reported in Syria and Iraq, likely against Iran-backed militias operating in those countries.
Shortly after the reported strikes, Iran fired air-defense batteries. Iranian officials said they fired at drones overhead, though they did not explicitly say Israel was responsible.
“The explosion this morning in the sky of Isfahan was related to the shooting of air defense systems at a suspicious object that did not cause any damage,” Iranian army commander Gen. Abdolrahim Mousavi.
The reported Israeli counterattack comes just days after Iran last Saturday fired more than 300 missiles and drones at Israel, the vast majority of which were shot down by Israeli and U.S. defenses.
That Iranian attack came as a response to an April 1 strike on a portion of the Iranian diplomatic complex in Damascus, Syria. That strike, believed to have been carried out by Israel, killed Islamic Revolutionary Guards Corps Gen. Mohammad Reza Zahedi and other Iranian officials.
SEE ALSO: Israel targets air defense system in Syria, state news agency says
Israeli officials vowed that they would respond to Iran‘s attack last weekend. If Thursday’s reports are true, the Israeli retaliation began with a strike in Isfahan along with the strikes in Syria and Iraq. That would mean Israel launched near-simultaneous strikes against Iranian and Iranian proxy targets in three countries.
In some ways, that would mark a significant escalation in the Middle East conflict. At the same time, neither country appeared eager Friday to rush into a full-blown war. Iranian state-run media reportedly sought to downplay the incident, while one anonymous Iranian official suggested to The Times of Israel that the attack may have been carried out by internal actors.
“The foreign source of the incident has not been confirmed,” the Iranian official said on condition of anonymity, the newspaper reported. “We have not received any external attack, and the discussion leans more toward infiltration than attack.”
But some Israeli officials left little doubt of their nation’s involvement. National Security Minister Itamar Ben Gvir, a noted Israeli hard-liner, described the apparent Israeli retaliation with one word.
“Lame!” he said on X, according to English-language media accounts.
The strike, while clearly designed to send a message about Israel‘s military capabilities, also may have been intentionally limited to avoid further escalation with Iran. The Biden administration, and other influential international actors, have pleaded with both nations to pull back from the brink of all-out war.
As the situation unfolded early Friday in Iran, the country’s semi-official Fars News Agency reported explosions near Isfahan’s airport.
“The cause of these sounds is still unknown, and investigations continue until the exact details of the incident are determined,” the news outlet said.
Isfahan is home to a major airbase for the Iranian military, as well as heavily-hardened sites associated with its nuclear program. An Israeli strike on Iranian nuclear sites would be a serious step on the part of Jerusalem. But Iranian media outlets reported Friday that all nuclear facilities were unharmed.
The Associated Press reported that commercial flights began diverting their routes early Friday morning over western Iran without explanation.
Israeli retaliation against targets inside Iran could dramatically escalate an already tense and dangerous situation in the Middle East. Both Iran and its proxies such as the Lebanese militant group Hezbollah have vowed to strike back against Israel if Jerusalem launched any attacks on Iran.
According to reporters in Israel, sirens warning of an aerial incursion were going off in northern Israel near the Lebanon border.
A top Iranian military officer early Friday said Tehran would launch an attack on Israel’s nuclear facility in the Negev Desert if its nuclear sites were to be targeted.
Brig. Gen. Ahmad Haqtalab, head of the Islamic Revolutionary Guard Corps’ Nuclear Facilities Protection and Security Command, told the state-owned Tasnim News Agency that Iran is prepared to confront any threat from Israel.
“The nuclear facilities of the Zionist enemy have been identified, and we have the necessary information about all the targets,” Gen. Haqtalab said. “Our fingers are on the trigger of powerful missiles to destroy the specified targets in response to their possible action.”
Gen. Haqtalab is likely referring to the Shimon Peres Negev Nuclear Research Center, located about 8 miles southeast of the city of Dimona in the Negev Desert.
Although security analysts believe the country has anywhere from 80 to 400 nuclear weapons, Israel’s official policy is that it won’t confirm or deny having any.
Launching strikes on Iranian soil would carry significant military risks for Israel. But some U.S. lawmakers say it’s highly possible that Israeli aircraft never entered Iranian airspace.
“Israel has the ability to conduct strikes against targets inside Iran without entering Iranian air space from aircraft over Syrian and Iraqi airspace,” Sen. Marco Rubio, Florida Republican, said in a post on X.
Tensions between Iran and Israel have been high for years, but they have neared a fever pitch in the months since Oct. 7, when the Iran-backed Palestinian militant group Hamas launched a terrorist attack that killed more than 1,200 Israelis.
• Mike Glenn contributed to this report.